RegRNA
A Regulatory RNA Motifs and Elements Finder
  Release 1.0, Jan 2006
 
 
 

Accession R0885
Feature Type Exonic Splicing RegRNA
Class Exon enhancer
Name Exon enhancer
Pattern AAGAAGGAAGG
BindingProtein Htra2‑�1, hnRNP‑G, SRp30c
References Hofmann Y, Lorson CL, Stamm S, Androphy EJ, and Wirth B
Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2).
Proc Natl Acad Sci U S A 2000; 97(17), 9618-23   PubMed 

DiDonato CJ, Lorson CL, De Repentigny Y, Simard L, Chartrand C, Androphy EJ, and Kothary R
Regulation of murine survival motor neuron (Smn) protein levels by modifying Smn exon 7 splicing.
Hum Mol Genet 2001; 10(23), 2727-36   PubMed 

Hofmann Y, and Wirth B
hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1.
Hum Mol Genet 2002; 11(17), 2037-49   PubMed 


Department of Biological Science and Technology, Institute of Bioinformatics, National Chiao Tung University, Taiwan
Contact with Dr. Hsien-Da Huang