RegRNA
A Regulatory RNA Motifs and Elements Finder
  Release 1.0, Jan 2006
 
 
 

Accession R0832
Feature Type Exonic Splicing RegRNA
Class Exon silencer
Name Exon silencer
Pattern CTAGACTAGA
BindingProtein hnRNP A1
References Caputi M, Mayeda A, Krainer AR, and Zahler AM
hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing.
EMBO J 1999; 18(14), 4060-7   PubMed 

Amendt BA, Si ZH, and Stoltzfus CM
Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors.
Mol Cell Biol 1995; 15(11), 6480   PubMed 

Si Z, Amendt BA, and Stoltzfus CM
Splicing efficiency of human immunodeficiency virus type 1 tat RNA is determined by both a suboptimal 3` splice site and a 10 nucleotide exon splicing silencer element located within tat exon 2.
Nucleic Acids Res 1997; 25(4), 861-7   PubMed 

Del Gatto-Konczak F, Olive M, Gesnel MC, and Breathnach R
hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer.
Mol Cell Biol 1999; 19(1), 251-60   PubMed 


Department of Biological Science and Technology, Institute of Bioinformatics, National Chiao Tung University, Taiwan
Contact with Dr. Hsien-Da Huang