RegRNA
A Regulatory RNA Motifs and Elements Finder
  Release 1.0, Jan 2006
 
 
 

Accession R0504
Feature Type Riboswitch
Name S-adenosylmethionine riboswitch
Regulatory Motif
(RNAMotif descriptor)
descr

	h5(seq="^YCUUAUC$")

		ss(seq="^NAGAG$")		

		ss(minlen=0, maxlen=2)

		h5(seq="^GGY$")

			ss(seq="^RGA$")

			h5(seq="^GGG$")

				ss(seq="^AYNGG$")

			h3

			ss(seq="^NNYGAN$")

		h3

		ss(seq="^C$")

		h5(seq="^RGC$")

			ss(seq="^AA$")

				h5(seq="^CNN$")

					h5(minlen=2, maxlen=3)

						ss(len=5)

					h3

					ss(seq="^R$")

				h3

			ss(seq="^U$")

		h3

		ss(seq="^AANUCCNR$")

		h5(seq="^CARR$")

			h5(minlen=2, maxlen=3)

				ss(len=5)

			h3

		h3

		ss(seq="^RRA$")

	h3
Ligand SAM (S-adenosylmethionine)
References Epshtein V, Mironov AS, and Nudler E
The riboswitch-mediated control of sulfur metabolism in bacteria.
Proc Natl Acad Sci U S A 2003; 100(9), 5052-6   PubMed 

Winkler WC, Nahvi A, Sudarsan N, Barrick JE, and Breaker RR
An mRNA structure that controls gene expression by binding S-adenosylmethionine.
Nat Struct Biol 2003; 10(9), 701-7   PubMed 

Winkler WC, and Breaker RR
Genetic control by metabolite-binding riboswitches.
Chembiochem 2003; 4(10), 1024-32   PubMed 

Mandal M, and Breaker RR
Gene regulation by riboswitches.
Nat Rev Mol Cell Biol 2004; 5(6), 451-63   PubMed 


Department of Biological Science and Technology, Institute of Bioinformatics, National Chiao Tung University, Taiwan
Contact with Dr. Hsien-Da Huang