RegRNA
A Regulatory RNA Motifs and Elements Finder
  Release 1.0, Jan 2006
 
 
 

Accession R0502
Feature Type Riboswitch
Name Flavin mononucleotide riboswitch
Regulatory Motif
(RNAMotif descriptor)
descr

	h5(seq="^YYYUC$")

		ss(seq="^RGGGC$")

		h5(seq="^NGGG$")

			ss(seq="^YGNAANU$")	

		h3

		ss(seq="^ACCG$")

		h5(seq="^GYGG$")

			ss(seq="^URN$")

			ss(minlen=5, maxlen=35)

			ss(seq="^AGY$")

		h3

		ss(seq="^GN$")

		ss(minlen=5, maxlen=35)

		ss(seq="^NGA$")

		h5(seq="^YYYRG$")

			ss(seq="^UKNRANK$")	

		h3

		ss(seq="^RCCGA$")

		h5(seq="^CRG$")

			ss(seq="^U$")

			ss(minlen=2, maxlen=3)

			ss(seq="^AGU$")

		h3

		ss(seq="^GAUGRRA$")

	h3

Ligand FMN (flavin mononucleotide)
References Gelfand MS, Mironov AA, Jomantas J, Kozlov YI, and Perumov DA
A conserved RNA structure element involved in the regulation of bacterial riboflavin synthesis genes.
Trends Genet 1999; 15(11), 439-42   PubMed 

Lee JM, Zhang S, Saha S, Santa Anna S, Jiang C, and Perkins J
RNA expression analysis using an antisense Bacillus subtilis genome array.
J Bacteriol 2001; 183(24), 7371-80   PubMed 

Vitreschak AG, Rodionov DA, Mironov AA, and Gelfand MS
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
Nucleic Acids Res 2002; 30(14), 3141-51   PubMed 

Winkler WC, Cohen-Chalamish S, and Breaker RR
An mRNA structure that controls gene expression by binding FMN.
Proc Natl Acad Sci U S A 2002; 99(25), 15908-13   PubMed 

Winkler WC, and Breaker RR
Genetic control by metabolite-binding riboswitches.
Chembiochem 2003; 4(10), 1024-32   PubMed 

Mandal M, and Breaker RR
Gene regulation by riboswitches.
Nat Rev Mol Cell Biol 2004; 5(6), 451-63   PubMed 


Department of Biological Science and Technology, Institute of Bioinformatics, National Chiao Tung University, Taiwan
Contact with Dr. Hsien-Da Huang