RegRNA
A Regulatory RNA Motifs and Elements Finder
  Release 1.0, Jan 2006
 
 
 

Accession R0038
Feature Type RegRNA in 5'-UTR
Name Protamine P1 3’UTR Y-Box recognition site (Protamine-YRS)
Regulatory Motif
descr

	ss(seq="^CA$")

	ss(minlen=0, maxlen=4)

	ss(seq="^WCCAYCNNA$")

	ss(minlen=0, maxlen=1)

	ss(seq="^CTCCTGCNTGA$")

Description Protamine (Prm) mRNAs are translationally repressed for several days during male germ cell differentiation. Translational delay of Prm-1 mRNA involves the binding of Y-Box proteins MSY2 and MSY4 to a conserved region in the 3’most nt of the 3’UTR. The consensus site, denoted Y-Box Recognition Site (YRS) has been defined by mutational analysis and tested by the yeast three-hybrid system.
References
MSY2 and MSY4 bind a conserved sequence in the 3 untranslated region of protamine 1 mRNA in vitro and in vivo.
Mol Cell Biol 2001; , 7010-9   PubMed 


Department of Biological Science and Technology, Institute of Bioinformatics, National Chiao Tung University, Taiwan
Contact with Dr. Hsien-Da Huang