||RegRNA in 5'-UTR
||Protamine P1 3’UTR Y-Box recognition site (Protamine-YRS)
||Protamine (Prm) mRNAs are translationally repressed for several days during male germ cell differentiation. Translational delay of Prm-1 mRNA involves the binding of Y-Box proteins MSY2 and MSY4 to a conserved region in the 3’most nt of the 3’UTR. The consensus site, denoted Y-Box Recognition Site (YRS) has been defined by mutational analysis and tested by the yeast three-hybrid system.
MSY2 and MSY4 bind a conserved sequence in the 3 untranslated region of protamine 1 mRNA in vitro and in vivo.
Mol Cell Biol 2001; , 7010-9   PubMed