A Regulatory RNA Motifs and Elements Finder
  Release 1.0, Jan 2006

Accession R0035
Feature Type RegRNA in 5'-UTR
Name Mos polyadenylation response element (Mos-PRE)
Regulatory Motif


Description During progesterone-stimulated Xenopus oocyte maturation, early cytoplasmic polyadenylation and translational activation of the Mos mRNA is mediated by a 24 nt region located at the 3'-end of Mos 3' UTR, termed a polyadenylation response element (PRE). The Mos PRE partially overlaps a downstream cytoplasmic polyadenylation element (CPE). The PRE appears to be conserved in other maternal Xenopus mRNAs, is responsive to the MAP kinase signaling pathway and is functionally distinct from the late-acting, cdc-2 responsive, cytoplasmic polyadenylation elements (CPEs).
A novel regulatory element determines the timing of Mos mRNA translation during Xenopus oocyte maturation.
EMBO J 2002; , 2798-806   PubMed 

Department of Biological Science and Technology, Institute of Bioinformatics, National Chiao Tung University, Taiwan
Contact with Dr. Hsien-Da Huang